Plastic injection protects mouse hearts after attack

 作者:姚泫蜷     |      日期:2019-03-07 06:10:01
MEND your broken heart with plastic. Injecting sticky polymer tags could one day limit tissue damage after heart attacks. Ways to control inflammatory monocytes – immune cells that can damage the body after a heart attack – have been elusive, says Stephen Miller at Northwestern University in Evanston, Illinois. His team found microparticles of the biodegradable polymer PLGA, which is already used for dissolvable sutures, can tag monocytes in mice and remove them from inflamed sites (Science Translational Medicine, Injecting the tags halved the size of lesions after a heart attack. Mice with other inflammatory diseases, including West Nile virus, also improved after being injected. This article appeared in print under the headline “Bio-tags mend mice after heart attack” More on these topics: